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Another field of interest for SAXS application is the study of biological macromolecules (Bio-SAXS) since the scattering profile contains information about their size, shape and internal structure. This allows for the calculation of relevant structural parameters such as the molecular volume, the molecular mass or the radius of gyration.

The Bruker AXS NANOSTAR, with its intense, collimated primary beam and 2-dimensional detector, has a similar design to a synchrotron SAXS beamline. With a 2-dimensional detector, the misinterpretation of data due to a 0-D or 1-D data collection method is avoided, eliminating the need for restrictive initial assumptions about the sample. In fact, the NANOSTAR analyzes pure sample properties, even if the sample particles are asymmetric or show preferred orientation. Additionally, a real space image with µm SAXS resolution of the sample can be taken by performing Nanography. The NANOSTAR features a brilliant x-ray source, combined with innovative multi-layer optics, which provides an intense, point-like incident beam upon the sample. Also included is the HI-STAR detector, a virtually noise-free, real-time 2-d detector with photon counting ability.